If you’re craving smoother skin, refined pores, and a youthful glow—but don’t want the volume of fillers or the freeze of Botox—Rejuran might just be your holy grail. This Korean skin booster doesn’t mask imperfections—it heals your skin from within using cutting-edge DNA technology.
Let’s dive into everything you need to know about Rejuran: how it works, what it treats, and why so many dermatologists and beauty lovers are obsessed.
What Exactly Is Rejuran?
Rejuran is a polynucleotide (PN)-based injectable treatment derived from salmon DNA. These DNA fragments have been scientifically proven to be biocompatible with human skin and offer powerful skin-regenerating effects.
Unlike hyaluronic acid fillers, Rejuran doesn’t aim to add volume or plumpness. Instead, it stimulates your skin’s natural healing, improving elasticity, hydration, texture, and resilience over time.
It’s often nicknamed the “Healer Injection” in Korea for good reason—it works beneath the surface, triggering collagen production and tissue repair.
How Rejuran Works
The core of Rejuran’s magic lies in polynucleotides (PN), which are long chains of DNA fragments. Extracted from salmon sperm, these molecules help:
Boost collagen and elastin production
Repair damaged skin cells
Enhance microcirculation
Reduce inflammation
Strengthen the skin barrier
The treatment is delivered via microinjections into the dermis, where the active ingredients begin to activate your skin’s repair systems.
Did you know? Salmon DNA is almost identical to human DNA and is known for its regenerative abilities, making it a safe and effective ingredient for skin repair.
Dr. E. Taylor, Aesthetic Medicine Specialist
🎯 Rejuran Variants: Which One Is Right for You?
Rejuran has multiple formulations to suit different skin concerns:
Rejuran Healer: The original formulation – improves texture, hydration, and skin elasticity for overall rejuvenation.
Rejuran I: Designed for the thin, delicate skin around the eyes – tackles fine lines, crow’s feet, and dark circles.
Rejuran S: Specifically created for acne scars and deep indentations – promotes tissue regeneration and smooths the skin surface.
Rejuran HB: A hybrid formula that combines PN with hyaluronic acid – ideal for dry, dull skin that needs deep hydration and plumping.
Rejuran Tone-Up: Focuses on brightening and evening skin tone, especially for pigmentation and sun damage.
Benefits of Rejuran
Here’s why Rejuran is becoming a go-to skin solution:
Benefit
What It Improves
Collagen stimulation
Fine lines, wrinkles, sagging
Deep hydration
Dryness, flakiness, dullness
Scar repair
Acne scars, surgical scars
Barrier restoration
Redness, sensitivity, inflammation
Pore reduction
Enlarged or visible pores
Under-eye rejuvenation
Dark circles, fine lines
Skin brightening
Pigmentation, sun damage
Who Is Rejuran For?
Ideal Candidates:
25+ with early signs of aging
Acne-prone or scarred skin
Sensitive, dry, or stressed skin
People wanting to prevent wrinkles early
Post-laser, post-acne healing boost
“I use Rejuran for patients with chronic redness, post-acne scars, or those recovering from laser damage. It’s gentle, yet powerful.”
Dr. E. Taylor, Aesthetic Medicine Specialist
Not Recommended If:
You are pregnant or breastfeeding
You have active skin infections or eczema flare-ups
You have an autoimmune condition
What to Expect During Treatment
1. Consultation & Skin Prep
A dermatologist will assess your skin and choose the right formula. The treatment area is cleansed and numbing cream is applied for 30–40 minutes.
2. Injection Process
Rejuran is injected using microdroplet technique (like mesotherapy) or with a dermal injector. The process takes around 20–30 minutes.
3. Aftercare & Downtime
Expect tiny bumps and redness that resemble mosquito bites for 24–48 hours
Avoid makeup, alcohol, steam rooms, and vigorous exercise for 2–3 days
Results begin to show after 2–4 weeks, with best results after 3–4 sessions
Treatment Plan & Timeline
For optimal results, Rejuran is done as a series:
Session
Time Gap
Purpose
1st
Week 0
Initial activation
2nd
Week 3–4
Reinforce healing
3rd
Week 6–8
Deep collagen boost
4th
Week 10–12
Long-lasting results
Maintenance: Every 6–9 months
Side Effects and Safety
Rejuran is KFDA-approved, non-allergenic, and widely used across Asia and Europe. Side effects are minimal, especially when performed by a qualified provider:
Common
Rare
Redness, swelling
Bruising at injection site
Tiny bumps (resolve quickly)
Mild sensitivity
Slight discomfort
Infection (if poor aftercare)
Pricing: What Does Rejuran Cost?
Country
Average Price / Session
South Korea
$200–$300
Singapore
$350–$500
USA / Canada
$400–$700
Europe
€300–€450
Clinics may offer bundle packages for 3–4 sessions with discounts.
Best Aftercare Products to Pair
Post-Rejuran, your skin needs soothing, hydrating, and barrier-supporting products:
Cicaplast Baume B5 (La Roche-Posay)
Avene Cicalfate+ Cream
Hyaluronic Acid Serums (without fragrance or alcohol)
SPF 50+ — a must for daily use!
Final Thoughts
Rejuran is more than just a trend—it’s a science-backed way to repair and regenerate your skin on a cellular level. Whether you’re fighting early signs of aging, dealing with post-acne damage, or just want that glowing “glass skin” look, Rejuran offers a natural, non-invasive solution.
By LP Skin Team 
